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GLP-1 Exit Strategy

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Free Clinical Tool · Mounjaro · Wegovy · Ozempic · Saxenda

What happens to your body after stopping weight-loss medication — week by week.

Enter your medication and last dose date. Get a personalised clinical timeline of what to expect — and a specific action plan for your phase.

Built by an NHS A&E doctor with a decade in metabolic medicine. Not generic wellness content. Clinical depth, plain language.

weight regained in 12mo
without a plan (STEP 4)
~2wks until appetite typically
begins returning
5 distinct phases
mapped clinically

Clinical appointments via CQC-registered Sutton Medical Consulting

Free Timeline Tool
Your personalised GLP-1 withdrawal timeline

Educational tool. Not personal medical advice. If you have diabetes, are pregnant, or feel unwell — speak to your clinician.

Your current phase
Your full report includes
  • Why appetite returns when it does — the pharmacology explained plainly
  • Your week-by-week action plan (food, training, tracking)
  • The muscle loss mechanism and how to counter it
  • Early warning signs that your plan is drifting
  • A clinician note written for your specific phase
Get your full personalised report — free.
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Your Personalised GLP-1 Exit Report

Your 12-week transition plan

D
A note from Dr Dan Reardon · NHS A&E Doctor · GMC 6098984

"What you're navigating right now is one of the least well-supported transitions in modern medicine. The prescription is easy to get. The off-ramp isn't. This report is designed to change that — to give you the clinical framework that most patients never receive."

Dr Dan Reardon MB ChB, BSc (Anatomy), MSc (Mental Health)
Clinical Context — Why This Happens

Why appetite returns after stopping

What People Notice At This Stage

Common experiences

    Your Priority Actions This Week

    What to focus on now

      Your 12-week transition plan

      Early warning signs — act before it becomes a problem

      One quick question — so we can send you the right follow-up
      Got it. We'll send you content matched to where you are. ✓

      This report is the free version. The consultation is where the real work happens.

      A 60-minute Exit Strategy Review gives you a medically defensible written plan — specific to your history, your body, and your life. Not a protocol. A plan.

      £395
      60-minute review · Written plan · GP communication where appropriate Book your Exit Strategy Review →

      Via CQC-registered Sutton Medical Consulting · In-person or video

      Why This Tool Exists

      Most people stop GLP-1 medication without any guidance on what comes next.

      01

      The prescription is easy. The exit isn't.

      Private GLP-1 clinics are built to start treatment. Almost none are built to plan what happens when it stops. This tool fills that gap.

      02

      Appetite return is biology, not failure.

      GLP-1 drugs suppress appetite pharmacologically. When the drug clears, appetite returns. Understanding when and why it happens is the first step to managing it.

      03

      The 12-week window is the critical one.

      The STEP 4 and SURMOUNT-4 trials both show weight regain accelerates in the first 3–6 months. This is when a plan matters most — and when most people have none.

      04

      Structure beats willpower every time.

      Appetite drive is a biological signal. Fighting it with willpower alone is a weak strategy. Building the right environment and routine before it returns is the correct approach.

      05

      Muscle loss is the hidden problem.

      GLP-1 drugs cause both fat and muscle loss. Stopping without a strength protocol accelerates further muscle loss — making weight regain faster and harder to reverse.

      06

      One consultation changes the odds.

      A single clinician-led exit review — covering tapering, monitoring, maintenance, and contingency — significantly changes the probability of maintaining results.

      The Evidence

      The trial data is unambiguous. Without a plan, most people regain.

      The STEP 4 trial — published in the New England Journal of Medicine in 2022 — followed patients who stopped semaglutide after 20 weeks. Within 12 months of stopping, participants had regained an average of two thirds of their lost weight. Cardiometabolic improvements reversed in parallel.

      SURMOUNT-4 (JAMA, 2024) showed a similar pattern with tirzepatide. Participants who switched to placebo regained significant weight while those who continued did not.

      This is not a failure of the medication. It is what happens when a pharmacological support is removed without anything in place to replace what it was doing. Appetite returns. Food noise returns. The old patterns return.

      The question is not whether this will happen. The question is what is in place to manage it when it does.

      of lost weight regained within 12 months of stopping semaglutide without a maintenance plan
      STEP 4 trial, New England Journal of Medicine, 2022
      ~50%
      of weight regained within 12 months after stopping tirzepatide vs continued treatment
      SURMOUNT-4 trial, JAMA, 2024
      ~1wk
      half-life of semaglutide — meaning appetite begins returning within 2–3 weeks of the last dose for most people
      FDA prescribing information
      About Dr Dan Reardon

      NHS A&E doctor. A decade in metabolic medicine. Built this because it didn't exist.

      This tool exists because the exit problem is real, well-evidenced, and almost entirely ignored by the systems that created it. Private GLP-1 prescribing has grown enormously. Exit planning has not kept pace.

      I work in NHS emergency medicine and run a private practice focused on deprescribing — GLP-1s, SSRIs, PPIs, statins, antihypertensives. What I see in both settings is the same: patients who were well-supported starting treatment and left to figure out the exit on their own.

      This tool is the free version of the clinical framework I use in practice. If you want the full version — with your history, your results, and a written plan specific to you — that's what the Exit Strategy Review is for.

      NHS A&E DoctorFrontline emergency medicine — active
      MB ChB · BSc · MScCardiff & Birmingham
      GMC 6098984Fully registered
      Deprescribing SpecialistGLP-1s, SSRIs, PPIs, statins, antihypertensives
      Former FitnessGenes CEO$10M+ venture-backed · 3,000+ direct results reviews
      CQC-Registered PracticeSutton Medical Consulting, Sutton Coldfield
      MediaNYT · Scientific American · GQ · NBC The Doctors · BBC Radio London

      You have already done the hard part. Don't lose it without a plan.

      Book your GLP-1 Exit Strategy Review and leave with a written plan for what comes next — specific to you, not a generic protocol.

      Book your Exit Strategy Review — £395

      Via CQC-registered Sutton Medical Consulting · Sutton Coldfield · Video available UK-wide