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Deprescribing · SSRIs · Antidepressants · Step-Down Plan

You started the antidepressant for a reason. Is that reason still there?

SSRIs are initiated for specific clinical indications. Those indications evolve. A structured, clinician-led step-down with the right psychological scaffolding in place is fundamentally different from abrupt stopping, and produces very different outcomes.

Full page coming soon
What this page will cover

The clinical case for a proper step-down plan.

SSRI discontinuation syndrome

What withdrawal from antidepressants actually feels like, how long it lasts, and how a gradual taper prevents it.

Which SSRIs are hardest to stop

Paroxetine has the shortest half-life of the SSRIs and the highest discontinuation risk. Venlafaxine, an SNRI rather than an SSRI, behaves similarly and is covered here for that reason. Fluoxetine is often the easiest. The approach differs for each.

Stability scaffolding

Sleep architecture, stress load, social support, and relapse prevention planning: the non-pharmacological framework that makes step-down sustainable.

How long to taper

Standard guidance recommends 4 weeks. For patients on long-term high doses, the evidence supports much slower reduction, sometimes over months.

Relapse vs withdrawal

The most important clinical distinction in SSRI step-down, and how to tell the difference if symptoms emerge during taper.

MSc Mental Health background

Dr Reardon's MSc in Mental Health directly informs how SSRI step-down is approached, with the pharmacological and psychological picture considered together.

In the meantime, if you have questions before this page is complete, contact the practice directly, or book a consultation online. Every enquiry is reviewed personally by Dr Dan Reardon.